イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0636名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 03:44:35.46ID:QADmwljz0 バカメクチンの「抗がん効果」は完全に0 バカメクチン５μMで40%の健康な免疫細胞が死ぬwwwww バカメクチン５μMで40%のがん細胞が死ぬwwwww つまりバカメクチンは無差別に細胞を殺すだけのただの毒で抗がん効果は完全に0wwwwwww
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0642名無しのアビガン(大阪府)(ﾜｯﾁｮｲ 2328-BfDy)2022/07/13(水) 03:57:28.61ID:EdjxaR0n0 イベルメクチンによるHippo経路を標的とした新しい胃癌腹膜播種治療法の確立
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0645名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 04:03:08.77ID:QADmwljz0>>643 これ知らなかった奴って死にたくならねえのかな？ 俺ならとっくに自殺してるわwww
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0668名無しのアビガン(茸)(ｽﾌﾟﾌﾟ Sd43-4tB7)2022/07/13(水) 11:28:30.83ID:i+z4GB/Ld 今日も深夜から徹夜で5chバイトの書き込みの仕事に打ち込む工作員ww 一方、今日も教授として、研究者として忙しい花木教授であった
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0680名無しのアビガン(茸)(ｽﾌﾟﾌﾟ Sd43-4tB7)2022/07/13(水) 19:38:03.96ID:i+z4GB/Ld>>670 あらゆる癌に効くイベルメクチン
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0682名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 19:40:42.16ID:QADmwljz0>>657-658
This journal operates a single anonymized review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. Editors are not involved in decisions about papers which they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups. 0689名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:28:28.18ID:QADmwljz0 そもそも査読なんて意味ないけどなwwww 小保方晴子が査読に通ってNatureに載ったことすら低学歴は知らなかったらしいwwww
Our current observation allows us to communicate for the first time the in vitro evaluation of DNA damage produced by these antiparasiticides: a brief 80 min pulse-treatment of 5.0–50.0 μg/ml of IVM or 25.0 and 50.0 μg/ml of ivomec®, resulted in a manifest level of single DNA-strand break induction. This findings are in concordance with previous observations showing a genotoxic effect exerted by the abamectin, the most active form of the avermectin (avermectin B1a), able to induce single strand DNA breaks in rat hepatocytes from rats treated in vivo [27].
IVM reduced testicular volume, tubular diameter and germinal epithelium height. Spermatogenesis interruption, such as degeneration morphology of the germ cells
The results revealed that IVM increased the frequency of epithelial tumor in D. melanogaster considering all evaluated concentrations, while AMX showed no carcinogenic effect. 0692名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:29:12.47ID:QADmwljz0 イベルメクチンが人間の細胞でもDNA破壊することを確認！ 人間での発がん性確定wwwww
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0693名無しのアビガン(神奈川県)(ﾜｯﾁｮｲ cdee-TkQT)2022/07/13(水) 20:29:17.93ID:QhpJ88Ff0 >634 >637 >643 本当に夢のクリスやなぁ 0694名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:29:49.12ID:QADmwljz0 どんな生物種の細胞で試しても必ず発がん性がある もちろん人間の細胞でも発がん性は再現されてる これが毒メクチンwwww 0695名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:30:07.93ID:QADmwljz0>>693 あと途上国の「自称臨床試験」は臨床試験とは呼べないからねwww 同じ「臨床試験」を10個やってたまたま結果が偶然よく見えるやつだけ公表とか出来ちゃうからwwwww
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0699名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:30:56.93ID:QADmwljz0 低学歴って査読の意味すら知らなかったのなwwwww 0700名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:31:17.87ID:QADmwljz0>>685 >>>681 >査読もされてない中国の論文ww
This journal operates a single anonymized review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. Editors are not involved in decisions about papers which they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups. 0701名無しのアビガン(茸)(ｽﾌﾟﾌﾟ Sd43-4tB7)2022/07/13(水) 20:31:38.96ID:i+z4GB/Ldhttps://twitter.com/hanakihideaki/status/1546067329737318400?s=20&t
This journal operates a single anonymized review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. Editors are not involved in decisions about papers which they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups. 0708名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:34:39.58ID:QADmwljz0 バカメクチンの「抗がん効果」は完全に0 バカメクチン５μMで40%の健康な免疫細胞が死ぬwwwww バカメクチン５μMで40%のがん細胞が死ぬwwwww つまりバカメクチンは無差別に細胞を殺すだけのただの毒で抗がん効果は完全に0wwwwwww
イベルメクチンは広範な哺乳類の細胞に対して細胞生存率を著しく下げる毒性がある According to reports, IVM (1–280 μΜ) can significantly inhibit the cell viability of widely spread non-target mammalian cells (Molinari et al., 2009b, 2013). 本研究では人間の培養細胞に対してイベルメクチンがオートファジーを引き起こし細胞死を促すと判明 In the present study, we found that IVM-mediated proliferation inhibition in HeLa cells were markedly reverted by the addition of 3-MA. The result reflects that IVM can promote cell death by inducing autophagy in HeLa cells. イベルメクチンの細胞毒性メカニズムはAMPK/mTOR由来オートファジーおよびDNA酸化ダメージである可能性がある The mechanism of ivermectin’s cytotoxicity might be the AMPK/mTOR mediated autophagy and oxidative DNA damage. https://www.sciencedirect.com/science/article/pii/S0045653520316428?casa_token=grsoFiHgtasAAAAA:Rw1IbmA3vgPKjiGokdnzHyA5Rn0AeNvf7fruBmCUCJ2D2K0bUWw6wI7sTrQo4A8MTAo0n3-J0hZF0710名無しのアビガン(東京都)(ﾜｯﾁｮｲW cb58-KG4v)2022/07/13(水) 20:36:17.36ID:QADmwljz0 バカ里大学でヘルシンキ宣言を教えてないのに自主的に調べて理解してることを卒業の基準にしたら 卒業出来るやつ5000人に1人も居ねえだろw それ出来るならもっとマシな大学受かってるからな 0711名無しのアビガン(茸)(ｽﾌﾟﾌﾟ Sd43-4tB7)2022/07/13(水) 20:37:05.40ID:i+z4GB/Ld そういえば抗体研究のスペシャリストの東京理科大学名誉教授の村上康文教授も同じような事言ってたなw
