Cyber Shadow - Yacht Club Games
Unpacking - Humble Games
Tetris Effect: Connected - Enhance
Stick Fight: The Game - Landfall Games
Curse of the Dead Gods - Focus Home Interactive
Ender Lilies - Binary Haze Interactive
Doki Doki Literature Club Plus! - Serenity Forge
Spelunky 2 - Mossmouth
Road 96 - DigixArt Entertainment
Subnautica/Subnautica: Below Zero - Unknown Worlds Entertainment
Littlewood - SmashGames
Islanders - Coatsink Software
Slime Rancher: Plortable Edition - Monomi Park
Eastward - Chucklefish
Axiom Verge 2 - Thomas Happ Games

https://youtu.be/A9TtTXK4KK0

https://jp.gamesindustry.biz/article/2201/22010603/
https://www.gamesindustry.biz/articles/2022-01-04-nintendo-reveals-top-selling-indie-games-of-2021