Augmented antiviral T cell immunity by oral administration of IMM-124E in preclinical models and a phase I/IIa clinical trial: A method for the prevention and treatment of COVID-19 https://onlinelibrary.wiley.com/doi/10.1002/ddr.21890 健康な被験者への投与でT細胞を活性化しSARS-CoV-2スパイクタンパクへの 曝露時にインターフェロンγ産生の増加効果を示した臨床試験 0002名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FFbf-YC9L)2021/10/15(金) 22:30:00.68ID:k1/9JJHaF 【摂取を避けた方がよい・要注意な人】 ・ 牛乳アレルギー ・ 免疫抑制治療中(臓器移植など) ・ 妊娠中
【販売サイト】 iHerb https://jp.iherb.com/c/colostrum ハイマート https://www.heimat-ltd.com/item/healthfood (書き込み規制で直リンできないが) アマゾン・ヤフー・楽天等でも取扱あり 0003名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FFbf-YC9L)2021/10/16(土) 21:21:21.64ID:85/yQiVPF Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2 https://insight.jci.org/articles/view/145785 ラクダはMERS-CoVの中間宿主だが ラクダ乳にはMERS-CoV抗体が含まれ SARS-CoV-2に対しても交差反応し中和活性を示す 0004名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FFbf-YC9L)2021/10/18(月) 21:42:00.53ID:KxnqvFm/F Milk-derived anti-infectives and their potential to combat bacterial and viral infection https://www.sciencedirect.com/science/article/pii/S1756464621000918 > 4.1. Immunoglobulins > They are one of the most abundant bioactive proteins > ... 61.4 g/L in colostrum to 0.8 g/L in mature bovine milk
牛乳を日常的に多く飲む人であれば低温殺菌牛乳にするのもよいだろう とはいえサクッと摂取するには初乳サプリの方が効率的ではある 0005名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FFbf-YC9L)2021/10/20(水) 21:25:55.21ID:OGHfGMKpF RESEARCH CONDUCTED INTO HOW TO OBTAIN IMMUNE BOVINE MILK TO STRENGTHEN THE BODY AGAINST COVID-19 https://www.uco.es/ucci/es/noticias-ingles/item/3411-research-conducted-into-how-to-obtain-immune-bovine-milk-to-strengthen-the-body-against-covid-19 >This dairy preparation, which anyone can consume, >has already been tested on more than 300 people. >Amongst them, no serious Covid-19 process has been detected. >As soon as it goes on the market an observational test will be carried out.
順天堂大学などの研究 0011名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FFa2-r6B7)2021/10/22(金) 22:24:55.90ID:CYB5GMnJF Influences of bovine colostrum on nasal swab microbiome and viral upper respiratory tract infections - A case report https://www.sciencedirect.com/science/article/pii/S2213007120304032 ウシ初乳の効果に関する27歳の健康な男性ヨルダン人の症例報告
>There was no URTI episodes over the one-year following initiation of BC regimen >compared to 5 episodes past BC regimen over the previous year (p < 0.05).
投与前の1年間にURTI(上気道感染症≒風邪)を5回発症していたが投与開始後の1年間は発症せず
>Real-time qPCR showed there was a decrease in the nasal swab viral load >(indicated by a higher Ct value; from 19 to 25 cycles) 24 hours after the single BC regimen.
この人たちはシロです。 0019名無しのアビガン(東京都)(ﾜｯﾁｮｲW e1b9-r6B7)2021/10/28(木) 07:00:01.27ID:qnyGlpT30 Clinical evidence that the pandemic from 1889 to 1891 commonly called the Russian flu might have been an earlier coronavirus pandemic https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/1751-7915.13889
なおHCoV-OC43とBCoVは非常に近い 0025名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FF43-tE0W)2021/11/13(土) 23:40:00.19ID:bVg+bbVkF Perspectives on Immunoglobulins in Colostrum and Milk https://www.mdpi.com/2072-6643/3/4/442/htm https://www.mdpi.com/nutrients/nutrients-03-00442/article_deploy/html/images/nutrients-03-00442-g001-1024.png ヒト母乳中の抗体はIgAが多いが 他の動物では概してIgGが多い 0026名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FF43-tE0W)2021/11/14(日) 23:44:59.20ID:O2VXCW/uF Preexisting vs. de novo antibodies against SARS-CoV-2 in individuals without or with virus infection: impact on antibody therapy, vaccine research and serological testing https://transmedcomms.biomedcentral.com/articles/10.1186/s41231-021-00093-2 >individuals may have pre-existing antibodies to >recently emerged SARS-CoV-2 prior to the outbreak >due to infections with related common cold coronaviruses, > : >such antibodies may prove to be extremely beneficial >by providing pre-existing protective immunity to the hosts >when they bind to the conserved neutralizing epitopes >on the S2 domain of the spike protein.
この点はコロストラム中のBCoV抗体にも当てはまる 0027名無しのアビガン(公衆)(ｴﾑｿﾞﾈW FF43-tE0W)2021/11/16(火) 00:04:44.48ID:8quYQu0hF Molecular Epidemiology of Bovine Coronavirus on the Basis of Comparative Analyses of the S Gene https://journals.asm.org/doi/full/10.1128/JCM.44.3.957-960.2006 >In a nationwide survey of antibodies in bulk tank milk from >Swedish dairy herds, 89% of the samples were antibody positive >and 52% had high levels of antibodies to BCoV (15).
Bovine Coronavirus and the Associated Diseases https://www.frontiersin.org/articles/10.3389/fvets.2021.643220/full >The virus presence has been confirmed on all continents, >and seroprevalence studies demonstrate that over 90% of >cattle have been exposed to BCoV during their lifetime.
Seroprevalence of bovine coronavirus and factors associated with the serological status in dairy cattle in the western region of Thailand http://veterinaryworld.org/Vol.14/August-2021/8.html >The individual seroprevalence of BCoV was 97.89% (604/617).
Prevention of Influenza Episodes With Colostrum Compared With Vaccination in Healthy and High-Risk Cardiovascular Subjects: The Epidemiologic Study in San Valentino https://journals.sagepub.com/doi/10.1177/1076029606295957 >Colostrum, both in healthy subjects and high-risk cardiovascular patients, >is at least 3 times more effective than vaccination to prevent flu and is very cost-effective.
